Differential Regulation of TRPC4 in the vasopressin magnocellular system by water
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چکیده
Differential Regulation of TRPC4 in the vasopressin magnocellular system by water 1 deprivation and hepatic cirrhosis in the rat. 2 Running Head: TRPC4 regulation by water deprivation and hepatic cirrhosis 3 Authors: T. Prashant Nedungadi, J. Thomas Cunningham 4 5 Department of Integrative Physiology, and Cardiovascular Research Institute 6 University of North Texas Health Science Centre at Fort Worth, 7 3500 Camp Bowie Blvd 8 Fort Worth, TX 76107 9 10
منابع مشابه
Differential regulation of TRPC4 in the vasopressin magnocellular system by water deprivation and hepatic cirrhosis in the rat.
Transient receptor potential canonical subtype 4 (TRPC4) is expressed in the magnocellular paraventricular nucleus (PVN) and supraoptic nucleus (SON) of the hypothalamus. In this study, the regulation of TRPC4 expression was investigated in water deprivation and hepatic cirrhosis. We used laser capture microdissection technique for precise dissection of pure AVP cell population in the PVN and S...
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The activity of the magnocellular neurons (MCNs) of supraoptic nucleus (SON) is regulated by a variety of excitatory and inhibitory inputs. Opioids are one of the important compounds that affect these inputs at SON synapses. In this study, whole-cell patch clamp recording of SON neurons was used to investigate the effect of acute and repeated morphine administration on spontaneous inhibitory an...
متن کاملThe comparison of the effects of acute and repeated morphine administration on fast synaptic transmission in magnocellular neurons of supraoptic nucleus, plasma vasopressin levels, and urine volume of male rats
The activity of the magnocellular neurons (MCNs) of supraoptic nucleus (SON) is regulated by a variety of excitatory and inhibitory inputs. Opioids are one of the important compounds that affect these inputs at SON synapses. In this study, whole-cell patch clamp recording of SON neurons was used to investigate the effect of acute and repeated morphine administration on spontaneous inhibitory an...
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Introduction: The magnocellular neurons (MCNs) of the supraoptic nucleus (SON) play a crucial role in control of physiological and pathophysiologiccal condition due to two peptides that they synthesize, i.e. Oxytocin (OXT) and Vasopressin (AVP). The activity of MCNs is regulated by a variety of excitatory and inhibitory inputs. Opioid receptors are one of the important receptors in SON synap...
متن کاملThe Vasopressin Receptors Colocalize with Vasopressin in the Magnocellular Neurons of the Rat Supraoptic Nucleus and Are Modulated by Water Balance.
Activity of the magnocellular neurons that synthesize vasopressin in the supraoptic and paraventricular nuclei of the hypothalamus is modulated by local release of the neuropeptide within the nuclei. V(1a) and V(1b) vasopressin receptor genes are expressed in these cells. The present study reports the localization of V(1a) and V(1b) receptors using multiple labeling immunocytochemistry. Both re...
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